Ashpitel was architect of St James' Schoolhouse (or Mission Rooms) at Lea Bridge (by the earlier entrance to the Lea Bridge Waterworks).
He was also architect of St. Barnabas Church, Homerton (1845), later adding the parsonage (1848) and the north aisle and vestry (1852).
He completed works at the London Orphan Asylum in Clapton and the Wellington Testimonial at the Southwark end of London Bridge.
He was associated with John Whichcord with whom designed many churches, baths and washhouses in London and Kent.
He designed the Gravel Pit Chapel at Hackney and model artisans’ cottages, also in Hackney, schools for Holy Trinity, Hoxton, a gothic stone fronted public house in Redcross Street in the City and undertook research that informed Sir Charles Barry’s Charing Cross and designed the ornament cast on the Big Ben bell.
He was associated with architectural education and examination at the RIBA and the Architectural Association. The Ashpitel prize was named in his honour.
 The Architect, 30th January 1869, pages 64-65